In this chapter we go deep into HOW we and other living things were made by looking at our jeans?…no GENES.(: Even though we are made up of hundreds of different cells, they are all similar…WHAT? The way the gene acts makes it different. OH!
I love Shubin’s use of comparisons because they help me visualize what he’s saying on pg 46 he says “Like a concerto composed of individual notes played by many instruments, our bodies are a composition of individual genes turning on and off inside each cell during our development” this made complete and utter sense to me because I could visualize people playing the different instruments (:
I was really interested in reading how scientists in the 1950s and 1960s experimented on chicken eggs, and how a strip of tissue would base how the chicken’s arm would develop. And as previous students have blogged, THE ZPA IS VERY IMPORTANT. If everything goes right you have a perfect chicken, if something is slightly changed you get a horrific malformed chicken, and this also applies to all other limbed animals. Isn’t that just amazing?
So from the fly’s hedgehog gene, the scientists found the chicken’s hedgehog gene, and they named the chicken’s hedgehog gene Sonic hedgehog. The Sonic hedgehog is active in the ZPA tissue, which is how the gene turns on and off. When I read how the Skate-mouse experiment turned out I was so stunned. I knew that something would form, but when I saw the picture it was really different from the original fin. The new fin was separated in two..just AMAZING.
In my opinion I would have to disagree with Caroline, because this wasn’t my favorite chapter because it was a bit difficult to understand, although, it was a very interesting chapter because we learned how birth defects can occur; and like chapter one and two I learned something new (:
- Nikita Patel
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